Bufferin Premium Dx 60 Tablets Lion [Designated Class 2 Drug]

1. Pain relief for headaches, stiff shoulders, menstrual pain (menstrual pain), lower back pain, joint pain, neuralgia, muscle pain, sore throat, toothache, pain after tooth extraction, bruise pain, sprain pain, fracture pain, trauma pain, and ear pain.
2. Relief of fever during chills and fever

[Active ingredient] in 2 tablets
Ibuprofen: 160mg (Reduces pain and lowers fever.)
Acetaminophen: 160mg (Reduces pain and lowers fever.)
Anhydrous caffeine: 50mg (helps suppress pain and relieves headaches)
Dry aluminum hydroxide gel: 35mg (Protects the gastric mucosa and prevents stomach irritation.)
*Contains cellulose, hydroxypropyl cellulose, lactic acid, D-mannitol, potassium dihydrogen phosphate, silicon dioxide, Mg stearate, polyvinyl alcohol (partially saponified), talc, titanium oxide, glycerin fatty acid ester, and sodium lauryl sulfate as additives.

Avoid taking it on an empty stomach if possible, and wait at least 4 hours between doses.
Please take the following amount with water or lukewarm water.
●Adults (15 years and older): 2 tablets per dose, limited to 3 times per day.
●Under 15 years of age: Do not take
[Precautions regarding usage and dosage]
(1) Please strictly follow the directions and dosage.
(2) How to take out the tablet
As shown in the image, press the convex part of the PTP sheet containing the tablet firmly with your fingertips to break the aluminum foil on the back, then take it out and drink it.

1. Do not use the following people
(1) Persons who have had allergic symptoms due to this drug or its ingredients.
(2) People who have had asthma while taking this drug or other antipyretic analgesics or cold medicines.
(3) Children under 15 years of age.
(4) Pregnant women within 12 weeks of due date.
2. Do not take any of the following medicines while taking this drug:
Other antipyretic analgesics, cold medicines, sedatives, motion sickness medicines
3. Do not drink alcohol before or after taking the drug
4. Please do not use it for a long time

1. The following people should consult a doctor, dentist, pharmacist, or registered salesperson before taking the drug.
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(5) People who have had allergic symptoms due to medicines, etc.
(6) Persons who have received the following diagnosis. Heart disease, kidney disease, liver disease, systemic lupus erythematosus, mixed connective tissue disease
(7) Persons who have had the following diseases. Gastric/duodenal ulcer, ulcerative colitis, Crohn’s disease
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor, pharmacist, or registered salesperson with this document.
[Related areas: Symptoms]
Skin: Rash/redness, itching, and bruising.
Gastrointestinal: Nausea/vomiting, loss of appetite, stomach pain, stomach discomfort, stomatitis, heartburn, heaviness in the stomach, abdominal pain, diarrhea, bloody stool, gastrointestinal bleeding
Neuropsychiatric system: dizziness
Cardiovascular: palpitations
Respiratory: shortness of breath
Other: Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, difficulty in stopping bleeding, bleeding, back pain, excessive drop in body temperature, feeling tired
In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
[Symptom name: Symptom]
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis, acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sore lips, sore throat, extensive skin rash/redness, small bumps (pustules) appearing on reddened skin, general malaise, loss of appetite, etc. that persist or worsen rapidly.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may appear.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear.
Interstitial pneumonia: When you climb stairs or push yourself too hard, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc., which may appear suddenly or persist.
Aseptic meningitis: Symptoms include severe headache accompanied by stiffness in the neck, fever, nausea, and vomiting (these symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease).
Asthma: wheezing, whistling, and difficulty breathing when breathing.
Aplastic anemia: Bruises, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling sick and dizzy, blood in the urine, etc. may appear.
Agranulocytosis: Sudden onset of high fever, chills, sore throat, etc.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this document.
constipation, drowsiness
4. If your symptoms do not improve after taking 5 to 6 times, stop taking this medicine and consult your doctor, dentist, pharmacist, or registered salesperson with this document.
●There are different types of bufferin with different active ingredients. The antipyretic and analgesic ingredients of this product are ibuprofen and acetaminophen.
When consulting a doctor, dentist, pharmacist, or registered salesperson, please mention ibuprofen or acetaminophen.

(1) Store in a cool, dry place away from direct sunlight.
(2) Please keep out of reach of children.
(3) Do not replace it with another container (this may cause misuse or change the quality).
(4) Do not use products that have passed their expiration date.
(5) Be careful not to scratch the aluminum foil on the back of the tablets you are not taking, as this may cause deterioration.

Lion Co., Ltd. Customer Center
1-3-7 Honjo, Sumida-ku, Tokyo 130-8644
0120-813-752