Nexium Capsules 20 [Class 1 Drugs]

The most commonly reported adverse reactions include rash, dermatitis, abdominal pain, diarrhea, loose stool, abdominal distension, headache and taste abnormality. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

• respiratory distress, hives, facial/lips/tongue swelling[shock, anaphylaxis]
• general malaise, fever, shortness of breath, nose/subcutaneous bleeding[pancytopenia, agranulocytosis, hemolytic anemia, decreased platelets]
• nausea/vomiting, loss of appetite, yellowing of the skin and the white of eyes[fulminant hepatitis, liver dysfunction, jaundice, hepatic failure]
• fever, general malaise, rash/redness on the skin/eyes and in the mouth[toxic epidermal necrolysis, oculomucocutaneous syndrome]
• fever, cough, shortness of breath[interstitial pneumonia]
• fever, rash, joint pain, decreased urine output, edema[interstitial nephritis, acute renal disorder]
• muscle pain, stiffness and numbness of limbs, red-brown urine[rhabdomyolysis]
• nausea/vomiting, convulsion, headache, consciousness disorder[hyponatremia]
• confused consciousness and unable to have normal thoughts, impaired mind, hallucination[confusional state]
• difficulty in seeing letters or shapes, abnormal visual field[visual impairment]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

• Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
• To treat gastric/duodenal/anastomotic ulcer or Zollinger-Ellison syndrome: In general, for adults, take 1 capsule (20 mg of esomeprazole) at a time, once a day. The usual duration of administration is up to 8 weeks for gastric/anastomotic ulcer, and up to 6 weeks for duodenal ulcer.
  In general, for children whose body weight is 20 kg or over, take 10 to 20 mg of esomeprazole at a time, once a day, according to the symptoms. The usual duration of administration is up to 8 weeks for gastric/anastomotic ulcer, and up to 6 weeks for duodenal ulcer.
  To treat reflux esophagitis: In general, for adults, take 1 capsule (20 mg of esomeprazole) at a time, once a day. The usual duration of administration is up to 8 weeks. For maintenance therapy of repeatedly recurrent/relapsing reflux esophagitis, take 10 to 20 mg of esomeprazole at a time, once a day.
  In general, for children whose body weight is 20 kg or over, take 10 to 20 mg of esomeprazole at a time, once a day, according to the symptoms. The usual duration of administration is up to 8 weeks. For maintenance therapy of repeatedly recurrent/relapsing reflux esophagitis, take 10 mg of esomeprazole at a time, once a day. For children aged 1 year or over whose body weight is 20 kg or over, the dosage may be increased up to 1 capsule (20 mg of esomeprazole) at a time, according to the symptoms.
  For suppression of recurrence of gastric/duodenal ulcer associated with nonsteroidal anti-inflammatory drug or low-dose aspirin medication: In general, for adults, take 1 capsule (20 mg of esomeprazole) at a time, once a day.
  To help the eradication of Helicobacter pylori: In general, for adults, take 1 capsule (20 mg of esomeprazole) concomitantly with 750 mg of amoxicillin hydrate (titer) and 200 to 400 mg of clarithromycin (titer) at a time, twice a day, for 7 days.
  If this is insufficient, as an alternative, take 1 capsule (20 mg of esomeprazole) concomitantly with 750 mg of amoxicillin hydrate (titer) and 250 mg of metronidazole at a time, twice a day, for 7 days.
  This preparation contains 20 mg of esomeprazole in a capsule.
  In any case, strictly follow the instructions.
• If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should not take two doses at one time.
• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
• Do not stop taking this medicine unless your doctor instructs you to do so.

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
  If you have liver dysfunction.
• If you are pregnant or breastfeeding.
• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

• Keep out of the reach of children. Store at room temperature (1 to 30 degrees Celsius) away from direct sunlight and moisture.
• Discard the remainder. Do not store them. If you do not know how to discard, seek advice of your pharmacy or medical institution. Do not give the unused medicines to others.