Pyron Pl Granules Pro 12 Packs Shionogi Healthcare [Designated Class 2 Drug]

Relief of cold symptoms (sore throat, fever, runny nose, stuffy nose, sneezing, chills (chills due to fever), headache, joint pain, muscle pain)

It is a white granule containing the following ingredients in 4 packets (1g x 4, daily dose for an adult).
Salicylamide…1080mg
(suppresses pain and lowers fever)
Acetaminophen…600mg
(suppresses pain and lowers fever)
Anhydrous caffeine…240mg
(helps to suppress pain)
Promethazine methylene disalicylate…54 mg
(Prevent runny nose, stuffy nose, and sneezing)

[Additives]
Contains lactose hydrate, corn starch, sodium chloride, white sugar, and hydrated silicon dioxide.

Adults (15 years and older): Take 1 packet at a time, 4 times a day, after each meal and before bedtime, at least 4 hours apart.

[Age: Dose: Number of doses per day]
Adults (15 years and older): 1 packet: 4 times
Children under 15 years old: Do not give this product

●Please strictly follow the prescribed usage and dosage.

1. Do not use the following people
(1) Persons who have had allergic symptoms due to this drug or its ingredients
(2) People who have had asthma while taking this drug or other cold medicines or antipyretic analgesics.
(3) Persons with the following diagnosis: difficulty urinating, gastric/duodenal ulcer, glaucoma
(4) Children under 15 years old
2. If you are taking this drug, please do not use any of the following medicines.
Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicine, allergy medicines, etc.)
3. Do not drive a vehicle or operate machinery after taking this medicine. (Drowsiness may occur.)
4. Do not drink alcohol before or after taking the drug
5. Please do not use it for a long time

1. The following people should consult a doctor, pharmacist, or registered salesperson before taking the drug.
(1) Persons receiving treatment from a doctor or dentist
(2) People who are breastfeeding, pregnant, or think they are pregnant.
(3) Elderly people
(4) People who have had allergic symptoms due to drugs, etc.
(5) People with the following symptoms High fever
(6) People who have been diagnosed with the following: heart disease, liver disease, kidney disease, bronchial asthma
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor, pharmacist, or registered salesperson with this document.

[Related area: Symptoms]
Skin: Rash/redness, itching, edema
Blood: skin and mucous membranes turn dark purple, anemia
Gastrointestinal: Nausea/vomiting, loss of appetite, heartburn, abdominal pain, gastrointestinal bleeding
Neuropsychiatric system: dizziness, fatigue, headache, tinnitus, hearing loss, visual impairment, anxiety, irritability, insomnia, convulsions, mild clouding of consciousness, excitement, hallucinations, delusions
Respiratory: cough, difficulty breathing
Cardiovascular: hypertension, hypotension, tachycardia
Urinary system: difficulty urinating, urinary retention
Others: Excessive temperature drop, sweating, trembling, rhinitis symptoms, conjunctivitis

In rare cases, the following serious symptoms may occur: In that case, please see a doctor immediately.

[Symptom name: Symptom]
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Oculomucocutaneous syndrome (Stevens-Johnson syndrome): High fever, bloodshot eyes, eye discharge, sore lips, sore throat, widespread rash/redness on the skin, small bumps (pustules) appearing on reddened skin, general malaise, loss of appetite, etc. that persist or worsen rapidly.
Toxic epidermal necrolysis: High fever, bloodshot eyes, eye discharge, sore lips, sore throat, widespread rash/redness on the skin, small bumps (pustules) appearing on reddened skin, general malaise, loss of appetite, etc. that persist or worsen rapidly.
Acute generalized exanthematous pustulosis: High fever, bloodshot eyes, eye discharge, sore lips, sore throat, widespread rash/redness on the skin, small bumps (pustules) appearing on reddened skin, general malaise, loss of appetite, etc. that persist or worsen rapidly.
Aplastic anemia: Bruises, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling sick and dizzy, blood in the urine, etc. may appear.
Agranulocytosis: Sudden onset of high fever, chills, sore throat, etc.
Thrombocytopenia: A decrease in the number of platelets, a component of the blood, causes bleeding symptoms such as nosebleeds, bleeding from the gums, and bruising.
Asthma: wheezing, whistling, and difficulty breathing when breathing.
Interstitial pneumonia: When you climb stairs or push yourself too hard, you may experience shortness of breath, difficulty breathing, dry cough, and fever, which may appear suddenly or persist.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, and loss of appetite may occur.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear.
Rhabdomyolysis: Pain in the muscles of the limbs, shoulders, and lower back, numbness in the limbs, weakness, stiffness, general malaise, and reddish-brown urine.
Glaucoma attack: Sudden onset of redness, pain, blurred vision, headache, and nausea.

3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this document.
Dry mouth, drowsiness
4. If your symptoms do not improve after taking 5 to 6 times, please stop taking the drug and consult your doctor, pharmacist, or registered salesperson with this document.

1) Store in a cool, dry place away from direct sunlight.
(2) Please keep out of reach of children.
(3) Do not transfer to another container. (It may cause misuse or change in quality)
(4) Do not take the product after the expiration date.

Shionogi Healthcare Co., Ltd. “Medical Information Center”
2-6-18, Chuo-ku, Osaka, Osaka 541-0041
(Osaka): 06-6209-6948
(Tokyo): 03-3406-8450
Reception hours 9:00-17:00
(Excluding Saturdays, Sundays, and holidays)