{"id":86508,"date":"2025-03-19T13:04:41","date_gmt":"2025-03-19T04:04:41","guid":{"rendered":"https:\/\/apteka.jp\/shop\/januvia-tablets-50mg-class-1-drugs\/"},"modified":"2025-03-21T10:07:36","modified_gmt":"2025-03-21T01:07:36","slug":"januvia-tablets-50mg-class-1-drugs","status":"publish","type":"product","link":"https:\/\/apteka.jp\/ru\/shop\/januvia-tablets-50mg-class-1-drugs\/","title":{"rendered":"JANUVIA Tablets 50mg [Class 1 Drugs]"},"content":{"rendered":"<p><app-icon-heading class=\"c-product-detail-heading\" data-icon=\"alert-circle\"><\/p>\n<div class=\"c-icon-heading\" bis_skin_checked=\"1\">\n<h3 class=\"c-icon-heading__heading\">Possible adverse reactions to this medicine<\/h3>\n<\/div>\n<p><\/app-icon-heading><\/p>\n<p><raw-html data-content=\"The most commonly reported adverse reactions include hypoglycemia and constipation. If any of these symptoms occur, consult with your doctor or pharmacist.\"><span data-ref=\"content\">The most commonly reported adverse reactions include hypoglycemia and constipation. If any of these symptoms occur, consult with your doctor or pharmacist.<\/span><\/raw-html><\/p>\n<p><b><raw-html data-content=\"The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated <span class=&quot;c-product-detail-label c-product-detail-label--description&quot;>in brackets<\/span>. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.&#187;><span data-ref=\"content\">The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated <span class=\"c-product-detail-label c-product-detail-label--description\">in brackets<\/span>. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.<\/span><\/raw-html><\/b><\/p>\n<ul>\n<li><raw-html data-content=\"breathing difficulty, hives, swelling around eyes and lips<span class=&quot;c-product-detail-label&quot;>[anaphylactic reaction]<\/span>&#171;><span data-ref=\"content\">breathing difficulty, hives, swelling around eyes and lips<span class=\"c-product-detail-label\">[anaphylactic reaction]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"fever, erythema, bloodshot eyes<span class=&quot;c-product-detail-label&quot;>[Stevens-Johnson syndrome, dermatitis exfoliativa]<\/span>&#171;><span data-ref=\"content\">fever, erythema, bloodshot eyes<span class=\"c-product-detail-label\">[Stevens-Johnson syndrome, dermatitis exfoliativa]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"chills, craving for food, tremor in limbs<span class=&quot;c-product-detail-label&quot;>[hypoglycemia]<\/span>&#171;><span data-ref=\"content\">chills, craving for food, tremor in limbs<span class=\"c-product-detail-label\">[hypoglycemia]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"loss of appetite, general malaise, yellowness in skin or conjunctiva<span class=&quot;c-product-detail-label&quot;>[hepatic dysfunction, jaundice]<\/span>&#171;><span data-ref=\"content\">loss of appetite, general malaise, yellowness in skin or conjunctiva<span class=\"c-product-detail-label\">[hepatic dysfunction, jaundice]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"decreased urine output, general edema, malaise<span class=&quot;c-product-detail-label&quot;>[acute kidney injury]<\/span>&#171;><span data-ref=\"content\">decreased urine output, general edema, malaise<span class=\"c-product-detail-label\">[acute kidney injury]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"severe pain in the upper abdomen, back pain, nausea<span class=&quot;c-product-detail-label&quot;>[acute pancreatitis]<\/span>&#171;><span data-ref=\"content\">severe pain in the upper abdomen, back pain, nausea<span class=\"c-product-detail-label\">[acute pancreatitis]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"fever, dry cough, breathing difficulty<span class=&quot;c-product-detail-label&quot;>[interstitial pneumonia]<\/span>&#171;><span data-ref=\"content\">fever, dry cough, breathing difficulty<span class=\"c-product-detail-label\">[interstitial pneumonia]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"failure of passing stool, stomach ache, abdominal bloating<span class=&quot;c-product-detail-label&quot;>[intestinal obstruction]<\/span>&#171;><span data-ref=\"content\">failure of passing stool, stomach ache, abdominal bloating<span class=\"c-product-detail-label\">[intestinal obstruction]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"pain of the limb muscle, stiffness, numbness<span class=&quot;c-product-detail-label&quot;>[rhabdomyolysis]<\/span>&#171;><span data-ref=\"content\">pain of the limb muscle, stiffness, numbness<span class=\"c-product-detail-label\">[rhabdomyolysis]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"continuous bleeding, blue spot, subcutaneous bleeding<span class=&quot;c-product-detail-label&quot;>[thrombopenia]<\/span>&#171;><span data-ref=\"content\">continuous bleeding, blue spot, subcutaneous bleeding<span class=\"c-product-detail-label\">[thrombopenia]<\/span><\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"blister, erosion, erythema<span class=&quot;c-product-detail-label&quot;>[bullous pemphigoid]<\/span>&#171;><span data-ref=\"content\">blister, erosion, erythema<span class=\"c-product-detail-label\">[bullous pemphigoid]<\/span><\/span><\/raw-html><\/li>\n<\/ul>\n<p><raw-html data-content=\"The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.\"><span data-ref=\"content\">The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.<\/span><\/raw-html><\/p>\n<p><app-icon-heading class=\"c-product-detail-heading\" data-icon=\"feather\"><\/p>\n<div class=\"c-icon-heading\" bis_skin_checked=\"1\">\n<h3 class=\"c-icon-heading__heading\">Dosing schedule (How to take this medicine)<\/h3>\n<\/div>\n<p><\/app-icon-heading><\/p>\n<ul>\n<li><raw-html data-content=\"Your dosing schedule prescribed by your doctor is&amp;nbsp;((&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;&amp;nbsp;to be written by a healthcare professional))\"><span data-ref=\"content\">Your dosing schedule prescribed by your doctor is&nbsp;((&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;to be written by a healthcare professional))<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"<u>For patients with normal renal function or mild renal dysfunction<\/u> : In general, for adults, take 1 tablet (50 mg of sitagliptin) at a time, once a day. If the dose seems to be insufficient, it may be increased up to 2 tablets (100 mg) at a time, once a day, adequately monitoring the condition.<br \/><u>For patients with moderate renal dysfunction<\/u> : In general, for adults, take 25 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, it may be increased up to 1 tablet (50 mg) at a time, once a day, adequately monitoring the condition.<br \/><u>For patients with severe or end stage renal dysfunction<\/u> : In general, for adults, take 12.5 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, it may be increased up to 25 mg at a time, once a day, adequately monitoring the condition.<br \/>This medicine contains 50 mg of sitagliptin per a tablet. In either case, strictly follow the instructions. &#171;><span data-ref=\"content\"><u>For patients with normal renal function or mild renal dysfunction<\/u> : In general, for adults, take 1 tablet (50 mg of sitagliptin) at a time, once a day. If the dose seems to be insufficient, it may be increased up to 2 tablets (100 mg) at a time, once a day, adequately monitoring the condition.<br \/><u>For patients with moderate renal dysfunction<\/u> : In general, for adults, take 25 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, it may be increased up to 1 tablet (50 mg) at a time, once a day, adequately monitoring the condition.<br \/><u>For patients with severe or end stage renal dysfunction<\/u> : In general, for adults, take 12.5 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, it may be increased up to 25 mg at a time, once a day, adequately monitoring the condition.<br \/>This medicine contains 50 mg of sitagliptin per a tablet. In either case, strictly follow the instructions. <\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.\"><span data-ref=\"content\">If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.\"><span data-ref=\"content\">If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"Do not stop taking this medicine unless your doctor instructs you to do so.\"><span data-ref=\"content\">Do not stop taking this medicine unless your doctor instructs you to do so.<\/span><\/raw-html><\/li>\n<\/ul>\n<p><app-icon-heading class=\"c-product-detail-heading\" data-icon=\"alert\"><\/p>\n<div class=\"c-icon-heading\" bis_skin_checked=\"1\">\n<h3 class=\"c-icon-heading__heading\">\n                    The following patients may need to be careful when using<br \/>\n                    this medicine.<br \/>\n                    <br \/>Be sure to tell your doctor and pharmacist.<br \/>\n                  <\/h3>\n<\/div>\n<p><\/app-icon-heading><\/p>\n<ul>\n<li><raw-html data-content=\"If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.<br \/>If you have: ketosis, diabetic coma or precoma stage, type 1 diabetes, infection, injury, renal dysfunction, pituitary gland disorder, adrenal gland disorder, insufficient diet, a history of abdominal surgery or intestinal obstruction.<br \/>If you are in pre\/postoperative period or debilitated.<br \/>If you exercise intensely or drink a lot of alcohol.&#187;><span data-ref=\"content\">If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.<br \/>If you have: ketosis, diabetic coma or precoma stage, type 1 diabetes, infection, injury, renal dysfunction, pituitary gland disorder, adrenal gland disorder, insufficient diet, a history of abdominal surgery or intestinal obstruction.<br \/>If you are in pre\/postoperative period or debilitated.<br \/>If you exercise intensely or drink a lot of alcohol.<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"If you are pregnant or breastfeeding.\"><span data-ref=\"content\">If you are pregnant or breastfeeding.<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)\"><span data-ref=\"content\">If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)<\/span><\/raw-html><\/li>\n<\/ul>\n<p><app-icon-heading class=\"c-product-detail-heading\" data-icon=\"archive\"><\/p>\n<div class=\"c-icon-heading\" bis_skin_checked=\"1\">\n<h3 class=\"c-icon-heading__heading\">Storage conditions and other information<\/h3>\n<\/div>\n<p><\/app-icon-heading><\/p>\n<ul>\n<li><raw-html data-content=\"Keep out the reach of children. Store away from direct sunlight, heat and moisture.\"><span data-ref=\"content\">Keep out the reach of children. Store away from direct sunlight, heat and moisture.<\/span><\/raw-html><\/li>\n<li><raw-html data-content=\"Discard the remainder. Do not store them.\"><span data-ref=\"content\">Discard the remainder. Do not store them.<\/span><\/raw-html><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>This medicine inhibits enzyme that degrades incretin, blood glucose stabilizing substance. It consequently enhances insulinotropic action and effect of lowering glucagon level in state of hyperglycemia to improve blood glucose control.<br \/>\nIt is usually used to treat type 2 diabetes.<\/p>\n","protected":false},"featured_media":86909,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[8901],"product_tag":[],"class_list":{"0":"post-86508","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-internal","7":"pa_active-ingredient-sitagliptin-phosphate-hydrate","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/product\/86508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/comments?post=86508"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/media\/86909"}],"wp:attachment":[{"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/media?parent=86508"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/product_brand?post=86508"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/product_cat?post=86508"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/apteka.jp\/ru\/wp-json\/wp\/v2\/product_tag?post=86508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}