Bufferin Ex 10 Tablets Lion [Class 1 Drug]

1) Pain relief for headaches, lower back pain, joint pain, menstrual pain (menstrual pain), stiff shoulders, neuralgia, muscle pain, fracture pain, sprain pain, bruise pain, toothache, pain after tooth extraction, sore throat, earache, and trauma pain.
2) Relief of fever during chills and fever

1 tablet
Loxoprofen sodium hydrate…68.1mg (60mg as anhydrous)
(It suppresses pain such as headaches, back pain, joint pain, and menstrual pain, and also lowers fever.)
Dry aluminum hydroxide gel…120mg
(Protects the stomach mucosa and prevents stomach irritation.)
[Additives]
Contains lactose, hydroxypropyl cellulose, silicon dioxide, Mg stearate, and iron sesquioxide.
*Depending on the tablet, red spots may be seen due to additives.
[Notes regarding ingredients and amounts]
*Depending on the tablet, red spots may be seen due to additives.

●When symptoms appear, take the following dose as much as possible on an empty stomach, and wait at least 4 hours between doses.
●Please take with water or lukewarm water.
・Adults (15 years and older): 1 tablet at a time, up to 2 times a day. However, if symptoms occur again, you can take a third dose.
・Those under 15 years old: Do not take this product.
[Precautions regarding usage and dosage]
(1) Please strictly follow the directions and dosage.
(2) How to take out the tablet: Press the convex part of the PTP sheet containing the tablet firmly with your fingertips to break the aluminum foil on the back, take it out and drink it.
(If you accidentally swallow it whole, it may cause unexpected accidents such as getting stuck in the esophageal mucosa.)

1. Do not use the following people
(1) Persons who have had allergic symptoms due to this drug or its ingredients.
(2) People who have had asthma while taking this drug or other antipyretic analgesics or cold medicines.
(3) Children under 15 years of age.
(4) Persons receiving the following treatment at a medical institution. Stomach/duodenal ulcer, liver disease, kidney disease, heart disease
(5) A person whose doctor has pointed out a blood abnormality (blood disease) such as a low red blood cell count (anemia), a low platelet count (blood does not stop well or bleeds easily), or a low white blood cell count.
(6) Pregnant women within 12 weeks of due date.
2. Do not take any of the following medicines while taking this drug:
Other antipyretic analgesics, cold medicines, and sedatives
3. Do not drink alcohol before or after taking the drug
4. Do not take this medicine continuously for a long period of time (if symptoms such as pain recur even after taking it for 3 to 5 days, please stop taking it and consult a doctor).

1. The following people should consult a doctor, dentist, or pharmacist before taking the drug.
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(5) People who have had allergic symptoms due to medicines, etc.
(6) Persons who have received the following diagnosis. Bronchial asthma, ulcerative colitis, Crohn’s disease, systemic lupus erythematosus, mixed connective tissue disease
(7) Persons who have had the following diseases. Stomach/duodenal ulcer, liver disease, kidney disease, blood disease
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor or pharmacist with this document.
(1) If you experience symptoms such as an excessive drop in body temperature, weakness (lack of strength), or cold limbs (cold hands and feet) after taking an antipyretic analgesic such as this drug.
(2) If peptic ulcer or swelling appears after taking the product. In addition, in rare cases, serious symptoms such as gastrointestinal bleeding (vomiting of blood, nausea/vomiting, abdominal pain, black tar-like stool, bloody stool, etc.), gastrointestinal perforation (a hole in the gastrointestinal tract; nausea, vomiting, severe abdominal pain, etc.), and small/large intestine narrowing/obstruction (nausea/vomiting, abdominal pain, abdominal distention, etc.) may occur. In that case, please see a doctor immediately.
(3) If the following symptoms appear after taking the drug.
[Related areas: Symptoms]
Skin: Rash/redness, itching
Gastrointestinal: Abdominal pain, stomach discomfort, loss of appetite, nausea/vomiting, abdominal bloating, heartburn, stomatitis, indigestion
Cardiovascular system: increased blood pressure, palpitations
Neuropsychiatric system: drowsiness, numbness, dizziness, headache
Others: chest pain, fatigue, hot flashes on the face, fever, anemia, hematuria
●In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
[Symptom name: Symptom]
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Blood disorders: Sore throat, fever, general malaise, whitish appearance on the face and behind the eyelids, easy bleeding (bleeding gums, nosebleeds, etc.), bruising (color that does not disappear even when pressed), etc. may appear.
Oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis: High fever, bloodshot eyes, mucus, sore lips, sore throat, widespread rash/redness of the skin, etc. persist or worsen rapidly.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear.
Congestive heart failure: Symptoms include general malaise, palpitations, shortness of breath, chest discomfort, chest pain, dizziness, and fainting.
Interstitial pneumonia: When you climb stairs or push yourself too hard, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc., which may appear suddenly or persist.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may appear.
Rhabdomyolysis: Muscle pain in the limbs, shoulders, lower back, etc., numbness in the limbs, weakness, stiffness, general malaise, reddish-brown urine, etc.
Aseptic meningitis: Symptoms include severe headache accompanied by stiffness in the neck, fever, nausea, and vomiting (these symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease).
Asthma: wheezing, whistling, and difficulty breathing when breathing.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor or pharmacist with this document.
dry mouth, constipation, diarrhea
4. If your symptoms do not improve even after taking 1 to 2 times (this may be due to another disease), please stop taking this medicine and consult your doctor, dentist, or pharmacist with this document.

(1) Store in a cool, dry place away from direct sunlight.
(2) Please keep out of reach of children.
(3) Do not replace it with another container (this may cause misuse or change the quality).
(4) Do not use products that have passed their expiration date.
(5) Be careful not to scratch the aluminum foil on the back of the tablets you are not taking, as this may cause deterioration.

Lion Co., Ltd. Customer Center
1-3-7 Honjo, Sumida-ku, Tokyo 130-8644
0120-813-752