Colgen Kowa Ib Transparent Capsule Α Plus 18 Capsules Kowa [Designated Class 2 Drug]

Relief of cold symptoms (fever, sore throat, cough, phlegm, chills, headache, runny nose, stuffy nose, sneezing, joint pain, muscle pain)

(in 6 capsules) Ibuprofen 600mg
Ambroxol hydrochloride 45mg
d-chlorpheniramine maleate 3.5mg
Dihydrocodeine phosphate 24mg
dl-methylephedrine hydrochloride 60mg
Anhydrous caffeine 40mg

[Additives]
Povidone, l-menthol, hypromellose (hydroxypropyl methylcellulose), potassium hydroxide, macrogol, gelatin, glycerin, paraben, yellow No. 5, polyoxyethylene hydrogenated castor oil, soy lecithin, medium chain fatty acid triglyceride

Please take the following amount with water or warm water preferably within 30 minutes after meals.
[Age: Dose: Number of doses per day]
Adults (15 years and older): 2 capsules: 3 times
Children under 15 years of age: Do not take

1. Do not use the following people
(1) Persons who have had allergic symptoms due to this drug or its ingredients.
(2) People who have had asthma while taking this drug or other cold medicines or antipyretic analgesics.
(3) Children under the age of 15.
(4) Persons receiving treatment or medication for the following illnesses at a medical institution.
Stomach/duodenal ulcer, blood disease, liver disease, kidney disease, heart disease, high blood pressure, people taking zidovudine (Retrovir)
(5) Pregnant women within 12 weeks of due date.
2. Do not use any of the following medicines while taking this drug.
Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicines, allergy medicines, etc.)
3. After taking this medicine, do not drive a vehicle or operate machinery (you may experience drowsiness, etc.)
4. If you are breastfeeding, please do not take this drug or avoid breastfeeding if you are taking this drug.
5. Do not drink alcohol before or after taking the drug
Do not take for more than 6.5 days

1. The following people should consult a doctor, pharmacist, or registered salesperson before taking the drug.
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) Elderly people.
(4) People who have had allergic symptoms due to medicines, etc.
(5) People who have the following symptoms. High fever, difficulty urinating
(6) Persons who have received the following diagnosis. Thyroid dysfunction, diabetes, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, bronchial asthma, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
(7) Persons who have had the following diseases. Gastric/duodenal ulcer, ulcerative colitis, Crohn’s disease, blood disease, liver disease, kidney disease
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor, pharmacist, or registered salesperson with this package insert.

[Related area: Symptoms]
Skin: Rash/redness, itching
Gastrointestinal: Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, stomach/abdominal bloating
Neuropsychiatric system: dizziness, insomnia, depressed mood
Cardiovascular: palpitations
Respiratory: shortness of breath
Urinary system: difficulty urinating
Others: Blurred vision, ringing in the ears, swelling, back pain, numbness

In rare cases, the following serious symptoms may occur: In that case, please see a doctor immediately.

[Symptom name: Symptom]
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Oculomucocutaneous syndrome (Stevens-Johnson syndrome): High fever, bloodshot eyes, mucus, sore lips, sore throat, and widespread rash/redness of the skin persist or worsen rapidly.
Toxic epidermal necrolysis: High fever, bloodshot eyes, mucus, sore lips, sore throat, and widespread rash/redness of the skin persist or worsen rapidly.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may occur.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in joints), diarrhea, etc. may occur.
Aseptic meningitis: Severe headache accompanied by stiffness in the neck, fever, nausea, and vomiting appear. (Such symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: When climbing stairs or pushing yourself too hard, you may experience shortness of breath or difficulty breathing, dry cough, and fever, which may appear suddenly or persist.
Asthma: wheezing, whistling, and difficulty breathing when breathing.
Blood disorders: Sore throat, fever, general malaise, whitish appearance on the face and behind the eyelids, easy bleeding (bleeding gums, nosebleeds, etc.), bruising (color that does not disappear even when pressed), etc. may appear.
Digestive disorders: Black stools, hematemesis, bloody stools, mucus-bloody stools (loose stools mixed with blood, mucus, and pus), etc. may occur.
Respiratory depression: Shortness of breath, difficulty breathing, etc. occur.

3. If you experience symptoms such as an excessive drop in body temperature, weakness (lack of strength), or cold limbs (cold hands and feet) after taking the drug, immediately stop taking the drug and consult your doctor, pharmacist, or registered salesperson with this package insert.
4. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this package insert.Constipation, dry mouth, drowsiness
5. If your symptoms do not improve after taking 5 to 6 times (especially if your fever persists for more than 3 days or if your fever recurs), please stop taking the medicine and consult your doctor, pharmacist, or registered salesperson with this package insert.

(1) Avoid high temperatures and store in a cool, dry place out of direct sunlight.
(2) Please keep out of reach of children.
(3) Do not transfer to another container. (It may cause misuse or change in quality.)
(4) Please be careful when storing and carrying the PTP to avoid tearing the aluminum foil or deforming the capsule inside.
(5) Do not take the product after the expiration date (written on the outer box).

Kowa Co., Ltd. Pharmaceutical Division Customer Consultation Center
3-4-14 Nihonbashi Honmachi, Chuo-ku, Tokyo 103-8433
03-3279-7755
Reception hours: Monday-Friday (excluding holidays) 9:00-17:00