Comprehensive Cold Medicine A “Kunihiro” 24 Capsules Kokando Pharmaceutical [Designated Class 2 Drug

Relief of cold symptoms (runny nose, stuffy nose, sneezing, sore throat, cough, sputum, chills, fever, headache, joint pain, muscle pain)

In daily dose (9 tablets)
Ibuprofen…450mg
(Relieves fever, headache, joint pain, and muscle pain.)
d-chlorpheniramine maleate…3.5mg
(It suppresses symptoms of sneezing, runny nose, and stuffy nose due to its antihistamine effect.)
Tipepidine hibenzate…75mg
(Relieves cough and makes it easier to release phlegm.)
dl-methylephedrine hydrochloride…60mg
(It expands the bronchi, calms coughs, and makes it easier to expel sputum.)
Potassium guaiacolsulfonate…250mg
(It helps cut the sputum better and makes it easier to get rid of it.)
Anhydrous caffeine…75mg
(It relieves headaches.)
Thiamine nitrate…25mg
(Supplements vitamin B1.)
Riboflavin…12mg
(Supplements vitamin B2.)
Contains cellulose, pregelatinized starch, crospovidone, and magnesium stearate as additives.
[Notes regarding ingredients and amounts]
Urine may turn yellow when taking this drug, but this is caused by riboflavin (vitamin B2), so there is no need to worry.

[Dosage/Dosage]
Please take the next dose as soon as possible within 30 minutes after meals without chewing with water or hot water.
Adults (15 years and older): 3 tablets per dose, 3 times per day
Children under 15 years of age: Do not take
[Precautions regarding usage and dosage]
(1) Please strictly follow the prescribed usage and dosage.
(2) How to take out the tablet
As shown in the image on the right, press firmly on the convex part of the PTP sheet containing the tablet with your fingertips to break the aluminum foil on the back, then take it out and drink.
(If you accidentally swallow it whole, it may pierce the esophageal mucosa or cause an unexpected accident.)

1. Do not take this medicine for the following people:
(1) Persons who have had allergic symptoms due to this drug or its ingredients.
(2) People who have had asthma while taking this drug or other cold medicines or antipyretic analgesics.
(3) Children under the age of 15.
(4) Pregnant women within 12 weeks of due date.
2. Do not use any of the following medicines while taking this drug.
Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, motion sickness medicine, allergy medicines, etc.)
3. Do not drive a vehicle or operate machinery after taking this medicine.
(You may experience drowsiness, etc.)
4. Do not drink alcohol before or after taking this medicine.
5. Do not take for more than 5 days.

1. The following people should consult a doctor, pharmacist, or registered salesperson before taking this medicine.
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) People who are breastfeeding.
(4) Elderly people.
(5) People who have had allergic symptoms due to medicines, etc.
(6) People who have the following symptoms.
High fever, difficulty urinating
(7) Persons who have received the following diagnosis.
Thyroid dysfunction, diabetes, heart disease, high blood pressure, liver disease, kidney disease, glaucoma, systemic lupus erythematosus, mixed connective tissue disease
(8) Persons who have had the following diseases.
Gastric/duodenal ulcer, ulcerative colitis, Crohn’s disease
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking the medicine immediately and consult your doctor, pharmacist, or registered salesperson with this package insert.
Related parts…Symptoms
Skin: Rash, redness, itching, and bruising occur.
Digestive system: Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stools
Mental nervous system… dizziness
Circulatory system… palpitations
Respiratory system…shortness of breath
Urinary system…difficulty urinating
Others…blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, difficulty in stopping bleeding, bleeding, back pain, excessive drop in body temperature, feeling tired
In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
Symptom name…Symptom
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Mucocutaneous oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis: High fever, bloodshot eyes, mucus, sore lips, sore throat, widespread rash/redness of the skin, etc. persist or worsen rapidly.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may appear.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear.
Aseptic meningitis: Severe headache accompanied by stiffness in the neck, fever, nausea, and vomiting appear. (Such symptoms are particularly common in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: When you climb stairs or push yourself too hard, you experience shortness of breath, difficulty breathing, dry cough, and fever, which appear suddenly or persist.
Asthma: wheezing, whistling, and difficulty breathing when breathing.
Aplastic anemia: Bruises, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling sick and dizzy, blood in the urine, etc. appear.
Agranulocytosis: Sudden onset of high fever, chills, sore throat, etc.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this package insert.
Constipation, dry mouth, drowsiness
4. If your symptoms do not improve after taking 5 to 6 times, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this package insert.

(1) Store in a cool, dry place away from direct sunlight.
(2) Please keep out of reach of children.
(3) To avoid misuse and maintain quality, please do not transfer to another container.
(4) Do not take products that have passed their expiration date.

Koukando Pharmaceutical Co., Ltd.
2-8-27 Nagasumotodori, Amagasaki, Hyogo Prefecture
Customer consultation desk 0120-023520