Estac Eve 60 Tablets Ss Pharmaceutical [Designated Class 2 Drug]

Relief of cold symptoms (sore throat, chills, runny nose, stuffy nose, sneezing, fever, headache, cough, sputum, joint pain, muscle pain)

[Ingredients]
9 tablets (daily dose)
Ibuprofen…450mg
Dihydrocodeine phosphate…24mg
dl-methylephedrine hydrochloride…60mg
Chlorpheniramine maleate…7.5mg
Anhydrous caffeine…75mg
Thiamine nitrate (vitamin B1 nitrate)…24mg
Ascorbic acid (vitamin C)…300mg
Additives: silicic anhydride, cellulose, lactose, white sugar, hydroxypropyl cellulose, hypromellose, macrogol, Ca carbonate, carnauba wax, Mg stearate, talc, titanium oxide, partially pregelatinized starch, pullulan, polyoxyethylene polyoxypropylene glycol

Take the following dose three times a day, preferably within 30 minutes after meals.
●Adults (15 years and older): 1 package per serving
●Under 15 years of age: Do not take this product.
[Precautions regarding usage and dosage]
Please strictly follow the directions and dosage.

1. Do not take this medicine for the following people:
(1) Persons who have had allergic symptoms due to this drug or its ingredients.
(2) People who have had asthma while taking this drug or other cold medicines or antipyretic analgesics.
(3) Children under 15 years of age.
(4) Pregnant women within 12 weeks of due date.
2. Do not use any of the following medicines while taking this drug:
Other cold medicines, antipyretic analgesics, sedatives, antitussive expectorants, oral medicines containing antihistamines, etc. (oral medicines for rhinitis, medicines for motion sickness, medicines for allergies, hypnotic sedatives, etc.)
3. Do not drive a vehicle or operate machinery after taking this medicine.
(Drowsiness, etc. may occur.)
4. Do not take this drug if you are breastfeeding, or avoid breastfeeding if you are taking this drug.
5. Do not drink alcohol before or after taking this medicine.
Do not take for more than 6.5 days.

1. The following people should consult a doctor, pharmacist, or registered salesperson before taking this medicine.
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) Elderly people.
(4) People who have had allergic symptoms due to medicines, etc.
(5) People who have the following symptoms. High fever, difficulty urinating
(6) Persons who have received the following diagnosis. Thyroid dysfunction, diabetes, heart disease, hypertension, liver disease, kidney disease, glaucoma, systemic lupus erythematosus, mixed connective tissue disease, respiratory dysfunction, obstructive sleep apnea syndrome, obesity
(7) Persons who have had the following diseases. Gastric/duodenal ulcer, ulcerative colitis, Crohn’s disease
2. If the following symptoms appear after taking this medicine, it may be a side effect, so please stop taking it immediately and consult your doctor, pharmacist, or registered salesperson with this instruction manual.
(Related area: Symptoms)
Skin: Rash/redness, itching, and bruising.
Gastrointestinal: Nausea/vomiting, loss of appetite, stomach discomfort, stomach pain, stomatitis, heartburn, heaviness in the stomach, gastrointestinal bleeding, abdominal pain, diarrhea, bloody stools
Neuropsychiatric system: dizziness
Cardiovascular: palpitations
Respiratory: shortness of breath
Urinary system: difficulty urinating
Other: Blurred vision, ringing in the ears, swelling, nosebleeds, bleeding gums, difficulty in stopping bleeding, bleeding, back pain, excessive drop in body temperature, feeling tired
In rare cases, the following serious symptoms may occur. In that case, please see a doctor immediately.
(Symptom name: Symptom)
Shock (anaphylaxis): Immediately after taking the drug, symptoms such as itchy skin, hives, hoarseness, sneezing, itchy throat, difficulty breathing, palpitations, and clouded consciousness may occur.
Oculomucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis: High fever, bloodshot eyes, mucus, sore lips, sore throat, widespread rash/redness of the skin, etc. persist or worsen rapidly.
Liver dysfunction: Fever, itching, rash, jaundice (yellowing of the skin and whites of the eyes), brown urine, general malaise, loss of appetite, etc. may appear.
Kidney disorder: Fever, rash, decreased urine output, general swelling, general malaise, joint pain (pain in the joints), diarrhea, etc. may appear.
Aseptic meningitis: Symptoms include severe headache with stiffness in the neck, fever, nausea, and vomiting. (Such symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: When you climb stairs or push yourself too hard, you may experience shortness of breath, difficulty breathing, dry cough, fever, etc., which may appear suddenly or persist.
Asthma: wheezing, whistling, and difficulty breathing when breathing.
Aplastic anemia: Bruises, nosebleeds, bleeding gums, fever, pale skin and mucous membranes, fatigue, palpitations, shortness of breath, feeling sick and dizzy, blood in the urine, etc. may appear.
Agranulocytosis: Sudden onset of high fever, chills, sore throat, etc.
Respiratory depression: Shortness of breath, difficulty breathing, etc. appear.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen, please stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this instruction manual.
Constipation, dry mouth, drowsiness
4. If your symptoms do not improve even after taking 5 to 6 times (especially if your fever persists for more than 3 days or occurs repeatedly), stop taking this medicine and consult your doctor, pharmacist, or registered salesperson with this instruction manual.

(1) Store the bottle in a cool, dry place away from direct sunlight with the lid tightly closed.
(2) Please keep out of reach of children.
(3) Do not transfer to another container. (This may cause misuse or change in quality.)
(4) Do not handle this agent with wet hands. If you handle it with wet hands, the sugar coating may become uneven or discolored.
(5) The padding inside the bottle is to prevent the tablets from being damaged during transportation. After opening, please remove it as it is no longer needed.
(6) Do not take any medicines that have passed their expiration date.

SS Pharmaceutical Co., Ltd.
Tokyo Opera City Tower, 3-20-2 Nishi-Shinjuku, Shinjuku-ku, Tokyo