Metgluco Tablets 500mg [Class 1 Drugs]

The most commonly reported adverse reactions include diarrhea, nausea, loss of appetite, abdominal pain and vomiting. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

• gastrointestinal symptoms such as nausea and vomiting, malaise, muscle pain[lactic acidosis]
• lassitude, hunger, sweating[hypoglycemia]
• general malaise, loss of appetite, yellowing of the skin and the white of eyes[liver dysfunction, jaundice]
• pain/stiffness/numbness in the muscles of the limbs[rhabdomyolysis]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

• Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
• For type 2 diabetes mellitus: In general, for adults, start with 1 tablet (500 mg of the active ingredient) in 2 to 3 divided doses a day, either just before or after meal. The maintenance dose should be decided by judging the effectiveness of the medicine. Standard maintenance dose is 1.5 to 3 tablets (750 to 1,500 mg) in 2 to 3 divided doses a day. For children 10 years or older, start with 1 tablet (500 mg of the active ingredient) in 2 to 3 divided doses a day, either just before or after meal. The maintenance dose should be decided by judging the effectiveness of the medicine. Standard maintenance dose is 1 to 3 tablets (500 to 1,500 mg) in 2 to 3 divided doses a day. The dosage may be adjusted according to the symptoms. The maximum dose is 4.5 tablets (2,250 mg) a day for adults, 4 tablets (2,000 mg) a day for children.
  For ovulation induction in polycystic ovary syndrome and regulated ovarian stimulation in assisted reproductive therapy for polycystic ovary syndrome: In general, in combination with other ovulation inducing drugs or ovarian stimulating drugs, start with 1 tablet (500 mg of the active ingredient) at a time, once a day. If tolerated, the dosage may be increased up to 3 tablets (1,500 mg of the active ingredient) in 2 to 3 divided doses a day. The dosage will be stopped before ovulation or egg collection.
  Strictly follow the instructions in any case.
• If you miss a dose, take the next dose at the next scheduled time. You should never take two doses at one time.
• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
• Do not stop taking this medicine unless your doctor instructs you to do so.

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
  If you ever had lactic acidosis.
  If you are a patient with renal/liver/pulmonary dysfunction, cardiovascular disorder, prone to hypoxemia, dehydration, gastrointestinal disorder, type 1 diabetes mellitus, infection, or pituitary gland/adrenal dysfunction.
  If you are in a state of ketosis, in a diabetic coma/precoma, or in perioperative period.
  If you are receiving dialysis.
  If you are injured, malnourished, starved, or debilitated.
  If you drink excessive alcohol.
• If you are pregnant, breastfeeding or possibly pregnant.
• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

• Keep out of the reach of children. Store at room temperature (1 to 30 degrees Celsius) away from direct sunlight and moisture.
• Discard the remainder. Do not store them. If you do not know how to dispose of it, please consult the pharmacy or medical institution where you received it. Please do not give it to others.