VALACICLOVIR TABLETS 500mg “DSEP” [Class 1 Drugs]

The most commonly reported adverse reactions include abdominal pain, diarrhea, abdominal discomfort, nausea, headache and renal disorder. If any of them occurs, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

• dyspnea, swelling of eyelids/lips/tongue, palpitation[anaphylaxis shock, anaphylaxis]
• fever, bleeding tendency, general malaise[blood disorder including pancytopenia/agranulocytosis]
• decreased urine output, edema, general malaise[acute renal disorder, tubulointerstitial nephritis]
• coma, hallucination, convulsion[neuropsychiatric symptom]
• conjunctival hyperemia, erythema with edema on the center, erosions of oral or pubic mucosa[toxic epidermal necrolysis, oculomucocutaneous syndrome]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

• Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
• [Adults]
  Herpes simplex: In general, for adults, take 1 tablet (500 mg of valaciclovir) at a time, twice a day.
  Suppression of onset of herpes simplex virus infection (herpes simplex) associated with hematopoietic stem cell transplantation: In general, for adults, take 1 tablet (500 mg) at a time, twice a day from 7 days prior to hematopoietic stem cell transplantation to 35 days after transplantation.
  Herpes zoster: In general, for adults, take 2 tablets (1,000 mg) at a time, 3 times a day.
  Chickenpox: In general, for adults, take 2 tablets (1,000 mg) at a time, 3 times a day.
  Suppression of recurrent genital herpes: In general, for adults, take 1 tablet (500 mg) at a time, once a day. The dosage or frequency of doses may be adjusted according to the symptoms.
  [Children]
  Herpes simplex: In general, for children who weigh more than 40 kg, take 1 tablet (500 mg of valaciclovir) at a time, twice a day.
  Suppression of onset of herpes simplex virus infection (herpes simplex) associated with hematopoietic stem cell transplantation: In general, for children who weigh more than 40 kg, take 1 tablet (500 mg) at a time, twice a day from 7 days prior to hematopoietic stem cell transplantation to 35 days after transplantation.
  Herpes zoster: In general, for children who weigh more than 40 kg, take 2 tablets (1,000 mg) at a time, 3 times a day.
  Chickenpox: In general, for children who weigh more than 40 kg, take 2 tablets (1,000 mg) at a time, 3 times a day.
  Suppression of recurrent genital herpes: In general, for children who weigh more than 40 kg, take 1 tablet (500 mg) at a time, once a day. The dosage or frequency of doses may be adjusted according to the symptoms.
  In any case, the dosage or frequency of doses may differ according to the underlying disease. Strictly follow the instructions.
• If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should not take two doses at one time.
• If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
• Do not stop taking this medicine unless your doctor instructs you to do so. In addition, if the symptoms are not improving or even worsened although you are taking this medicine as instructed, consult with your doctor or pharmacist.

• If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
  If you have: compromised immune function (malignant tumor, autoimmune disease, etc.).
  If you are prone to dehydration (such as the elderly and those with chickenpox).
  If you have renal disorder.
  If you are on dialysis.
• If you are pregnant or breastfeeding.
• If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

• Keep out of the reach of children. Store at room temperature (1 to 30 degrees Celsius) away from direct sunlight and moisture.
• Discard the remainder. Do not store them. If you do not know how to discard, seek advice of your pharmacy or medical institution. Do not give the unused medicines to others.